Objective: encouraging inter-disciplinary research and promoting sustainable interactions between research communities by stepping up existing measures.

Initiatives supported: key strategic projects providing added value in terms of cutting-edge research, jointly conducted by the site's LabEx facilities and Clusters of Excellence and, more broadly, involving different "Investments for the Future" projects on the Bordeaux site.

Co-financing is granted by the LabEx/Clusters entities or any PIA project involved for a period of 2 years.

2 editions with 3 projects selected in 2013 and 4 in 2014:

  • NanoTubesinBrain* (01/2014 to 12/2015) and ExtraBRAIN** (06/2014 to 06/2016): project involving the communities and expertise of LAPHIA and BRAIN.Objective: understanding the role of neuronal extracellular space in neuronal communication through optical nano-imaging.

*Image and characterize the ECS organization in pathological brain tissues using carbon nanotube imaging / and identifiying the role of ECS organization in regulating neuronal network (dys)function

** Interrogating the physiology and pathology of the brain's extracellular space using innovative nano-imaging techniques

  • LITAQ* (10/2013 to 10/2015): project involving the communities and expertise of LaScArBx and COTE. Objective: reconstructing the past mechanisms which restricted the evolution of Aquitaine's populations (plant, animal and human) and environments. This project was voluntarily limited to a first case study (the coastline of northern Médoc), on which the two LabEx entities had already worked on an individual basis.

*Form the Pleistocene to the Anthropocene: unveiling the past mechanisms underlying the evolution of populations (plant, animal and human) and environments to predict future responses. Example of the Aquitaine coastline (LITAC)

  • Advanced statistical methods for the analysis of multidimensional brain imaging databases (01/2014 to 10/2015): project involving the communities/expertise of CPU and TRAIL. Objective: studying the factors underlying hemispheric specialization (HS), in particular the lateralization of cognitive functions such as language and mental arithmetic, and explaining the variability encountered in the human population.
  • SuperClass*: project involving the communities/expertise of CPU and BRAIN.

*New methods of acquisition and classification for high content screening of membrane receptor organization and dynamics using super-resolution microscopy

  • MultiMat*: project involving the communities/expertise of LAPHIA, LaScArBx and CPU. Objective: improving heritage conservation by understanding the genesis and development of calcitic alterations on the walls of painted caves.

*Multiphysics study of heritage materials in their environmental context for conservation purposes

  • HL-MRI*: project involving the communities/expertise of TRAIL, CPU and BRAIN.

*Development of a new MRI methods to assess hippocampal layers as a potential imaging biomarker of memory impairment in early multiple sclerosis



Claire Gaugain
Research program manager

Tel : 05 40 00 67 82